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Shorb knew that the same liver extract was used to treat pernicious anemia (her father-in-law had died from the disease), and concluded that LLD could be developed as an assay method to identify the active compound

The average absorption rate of a oral supplement is only 45 % compared with 90% via an IM shot

Reported weekly weight-loss differences over placebo were small (in the range of -0.06 to -0.15 kg/week, depending on dose)

This means vegetarians and vegans are at a high risk of not getting enough each day

Vitamin B12 is found in animal foods, as well as some fortified foods that have added B12

Research community protocols typically restrict dosing to the morning